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Fibrous obliteration of appendix9/19/2023 The primary outcome measure was appendicitis confirmed by histopathology. Study population characteristics and the histopathology reports of the appendectomy specimens were retrieved from the computer records. Histological examination of appendix specimens is routinely done in our institution hence the need to correlate the histopathological findings with the clinical diagnosis of appendicitis.ĭata of patients who had appendectomies during the study period between January and December 2013 was retrieved from the surgical database. Arguments against the practice include the rarity of incidental pathologies that may impact on treatment and also the financial implications of routine histopathological assessments ( 5, 6). There is variation between institutions in the practice of routine histopathological examination of appendectomy specimens. Right iliac fossa pain can be a presenting complaint of different pathologies that may mimic appendicitis especially in the female population causing diagnostic difficulties and often leads to negative appendectomies. Delayed diagnosis of appendicitis could lead to complications like perforated appendix, peritonitis, sepsis, increased morbidity and mortality ( 3, 4). The diagnosis of appendicitis is largely clinical and appendectomy is the treatment of choice. Accepted for publication Apr 27, 2015.Īppendicitis is a common acute surgical emergency with over 40,000 cases in the UK every year ( 1) and the estimated life time risk of appendicitis in the USA is 8.6% and 6.7% for males and females respectively ( 2). Keywords: Appendectomy specimens histopathological review negative appendectomy rates (NARs) The findings of abnormal pathologies on histopathological examination of the appendix which could potentially impact on the management of the patients justify the current practice of routine histopathological examination of resected appendix. Adults (>16 years) represented 77.8% of the negative appendectomies.Ĭonclusions: The observed high rates of negative appendectomy in the female sex can be reduced by utilizing combined clinical assessment and diagnostic imaging modalities. The female sex accounted for 59.1% of the negative appendectomies. The negative appendectomy (normal appendix on histology) rate was 11.3%. Approximately 1.7% of the 238 specimens were abnormal pathologies other than inflammation of the appendix. Of the 238 resected appendix, 211 (88.7%) had histopathology findings consistent with appendicitis. The female sex accounted for 46.6% of all the patients. Adult patients (>16 years) represented 79.4% of the study population. The mean age of the patients was 32 years (range, 7-81 years). Results: A total of 238 appendectomies were performed during the study period. The Histopathology reports of appendectomy specimens were retrieved. Methods: This is a retrospective analysis of 238 appendectomies carried out in a single UK center between January and December 2013. The aim of this study is to correlate the histological findings of appendectomy specimens with the clinical diagnosis of acute appendicitis. Histopathological examination of the appendectomy specimens are routinely carried out. Policy of Dealing with Allegations of Research Misconductīackground: Acute appendicitis is a common presentation in surgical assessment units and appendectomy accounts for a large number of emergency operations in the UK.Policy of Screening for Plagiarism Process.
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